Validation of Pneumococcal Iron Acquisition (piaA) Gene for Accurate Identification of Streptococcus pneumoniae
نویسندگان
چکیده
منابع مشابه
Antibodies to the iron uptake ABC transporter lipoproteins PiaA and PiuA promote opsonophagocytosis of Streptococcus pneumoniae.
PiaA and PiuA are the lipoprotein components of the Pia and Piu Streptococcus pneumoniae iron uptake ABC transporters and are required for full virulence in mouse models of infection. Active or passive vaccination with recombinant PiuA and PiaA protects mice against invasive S. pneumoniae disease. In this study we have analyzed the antibody responses and mechanism of protection induced by PiuA ...
متن کاملValidation of urinary antigen test for Streptococcus pneumoniae in patients with pneumococcal pneumonia.
The study was undertaken to prospectively evaluate a Streptococcus pneumoniae urinary antigen test for diagnosis of pneumococcal pneumonia among patient and control groups between 2004 and 2006. Microbiological analysis for these patients included Gram staining for sputum, sputum and blood culture. Nonconcentrated urine samples were tested using an immunochromatographic assay, the NOW S.pneumon...
متن کاملEfficacy of multiplex PCR procedure for Iranian Streptococcus pneumoniae isolates
Background: Identifying regional types and evaluating the frequency of pneumococcal strains has become increasingly important especially in vaccination. The purpose of this study was the identification and frequency determination of our regional serotype and evaluation of the performance of recent type specific multiplex PCR for the diagnosis of streptococcus pneumonia serotypes. Methods: All ...
متن کاملIdentification of Streptococcus pneumoniae revisited.
The sensitivities and specificities of several different diagnostic assays for Streptococcus pneumoniae were assessed using 99 clinical isolates of S. pneumoniae and 101 viridans streptococci and were as follows: Pneumoslide, 99 and 87%, respectively; Directigen, 100 and 85%, respectively; Phadebact, 100 and 98%, respectively; deoxycholate drop test, 99 and 98%, respectively; deoxycholate tube ...
متن کاملThe Identification of Streptococcus pneumoniae
Streptococcus pneumoniae, pneumococcus, is an important human pathogen that causes both serious invasive infections, such as septicaemia, meningitis and pneumonia, as well as mild upper respiratory infections. It also belongs to the normal nasopharyngeal microbial flora. The purpose of this study was to compare bacteriological phenotypic methods with genetechnological methods in the identificat...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Indian Journal of Medical Microbiology
سال: 2018
ISSN: 0255-0857
DOI: 10.4103/ijmm.ijmm_18_274